For these engaged in opioid agonist remedy (OAT), cannabis might be an efficient method to scale back fentanyl publicity.
That’s the takeaway from a new study revealed this month within the journal Drug and Alcohol Dependence.
Drawing knowledge from “two community-recruited potential cohorts of people that use medication in Vancouver, Canada,” the researchers from the College of British Columbia, Heart of Substance Use stated they studied “the connection between hashish use and up to date fentanyl publicity” amongst OAT individuals between the years 2016 and 2018.
OAT is “an efficient therapy for dependancy to opioid medication akin to heroin, oxycodone, hydromorphone (Dilaudid), fentanyl and Percocet,” according to the Canadian research hospital Centre for Addiction and Mental Health, that “includes taking the opioid agonists methadone (Methadose) or buprenorphine (Suboxone)” as a part of an effort to forestall withdrawal and scale back cravings.
The analysis revealed in Drug and Alcohol Dependence was based mostly on “819 individuals on OAT who contributed 1989 observations over the research interval.” In keeping with the researchers, fentanyl publicity was “widespread.”
“On the baseline interview, fentanyl was detected in a majority of individuals,” the researchers wrote, saying that it was detected in 53 p.c of the individuals, however that general “hashish use was independently related to lowered chance of being just lately uncovered to fentanyl.”
“[W]e discovered that amongst greater than 800 individuals on OAT in Vancouver, Canada, use of hashish was longitudinally related to a considerably decrease threat of being uncovered to fentanyl. Given the magnitude of the overdose disaster within the U.S. and Canada and the substantial contributions of fentanyl to the burden of overdose morbidity and mortality, findings from this research assist the experimental analysis of cannabinoids as a possible adjunct remedy to OAT to enhance medical outcomes, significantly to cut back the chance of relapse to illicit opioid use (i.e., fentanyl) and related threat of overdose and loss of life,” the researchers wrote, as quoted by NORML.
The Position of Hashish In The Opioid Disaster
The research is the most recent in a rising physique of analysis to counsel that hashish could also be an efficient weapon within the combat towards the opioid disaster. And because the researchers within the aforementioned research famous, the “ongoing opioid overdose disaster is pushed largely by publicity to illicitly-manufactured fentanyl.”
In July, a study revealed within the journal Systematic Opinions discovered “a a lot increased discount in opioid dosage, lowered emergency room visits, and hospital admissions for power non-cancer ache by MC [medical cannabis] customers, in comparison with folks with no extra use of MC.”
“There was 64 to 75 p.c discount in opioid dosage for MC customers and full stoppage of opioid use for power non-cancer ache by 32 to 59 p.c of MC customers, when in comparison with sufferers with out extra use of MC,” the researchers of that research wrote.
And in June, research revealed within the Journal of Psychopharmacology discovered “behavioral financial proof that hashish entry could modestly scale back demand for opioids in individuals who’ve ache.”
“Adults reporting present use of opioids for ache administration and previous 30-day hashish publicity…accomplished two hypothetical buy duties by which solely grams of hashish or models of individuals’ index opioids had been accessible for buy, and two hypothetical duties by which each had been concurrently accessible and the worth of 1 drug elevated whereas the opposite was stored fixed,” the researchers wrote.